Hmm, are you a lumper or a splitter…? (:

Wayne Hollyoak

If this isn’t the case, name several cellular nanomachines that have been demonstrated to not have zero tolerance without any negative effects on creatures in the wild.

Wayne Hollyoak

Chromosome number is not what geneticists are talking about when they talk about similarity.

The inescapable fact is that chromosomes are very plastic, even within a species (including humans), and changes are observed in real time. You might try looking up “balanced translocation” for starters.

You’re also fudging when you try to blow this off as mere similarity. The thing you can’t explain is why classification of whole organisms as well as the sequences of their component proteins yields twin nested hierarchies. Darwin’s predictions about common descent apply to protein sequences, and even more importantly, protein families that evolve over multiple phyla. Do you even know what a phylum is?

That’s why pretending that this is mere similarity constitutes bearing false witness.

Even more importantly, I use the tweaks to do experiments on cells under the microscope, and my tweaks don’t have any phenotype in the whole animal.

So if your claim that these machines operate under conditions of zero tolerance, how is it that I can make a radical change in a residue in the active site without harming homozygous mutant animals?

How can other scientists take out whole segments to study biophysics, but the machines still work?

And why did God design the genes that encode them with all sorts of alternative splicing that makes multiple isoforms, many of them nonfunctional?

And why are those of us who actually are interested enough in these machines to study them laughing at people who bear false witness while being so lazy as to not study them at all before bloviating?

Wayne

I think you’re funny, Wayne.

“Most of them really have no idea how living things work.”

But as a biologist, it’s clear from what you write that you have no idea how living things work. How can you be so arrogant?

“Every living thing that we know of is full of tiny mechanical marvels we call nano machines.”

Those of us who are interested enough in them to study them instead of being dishonest about them to make political points (that would be you) don’t call them that. There are many different ones with many different names, and if you really had any idea how living things work, you’d have known that.

“Nano machines are so tiny that they are invisible to the naked eye. They operate at the molecular level where the tolerances are always ZERO.”

Your second sentence here is utterly, completely, spectacularly FALSE. What does your Bible say about bearing false witness, Wayne?

“Men are just starting to play with trying to fabricate nano machines. To build them requires electron microscopy and an obsurd amount of process control. One ATOM out of place can shut one down in many cases.”

Then you’ve got a problem, because biological machines are much more robust from that–moreover, that’s a prediction of modern evolutionary theory.

“Yet, these perfect/nanomachines run constantly and flawlessly in every cell of our bodies.”

More false witness, Wayne. They work via fuzzy logic, which means that at the level of individual “machines,” flawless function is neither needed nor ever observed.

“Every cell may contain thousands of them.”

You’re multiple orders of magnitude off here. If you think these nanomachines are so fascinating, why don’t you try, uh, studying them before pontificating?

“They are constantly being built and dismantled and the materials reused to make others. We can look at them and hope to understand what each one does, but never hope to reproduce one.”

Huh? I tweak them and get cells to reproduce them in unnatural ways. How can you write this hooey?

“Yes, each and every nano machine that exists in nature is proof (not just evidence) that we were all created by the wisest Person imaginable.”

I don’t see how, but then unlike you, I study them with a passion and for a living. For you, they appear to be a subject to spread falsehoods about.

nice blog and photo…